Mechanism of Iron Ion Homeostasis in Intestinal Immunity and Gut Microbiota Remodeling
Honghong Bao, Yi Wang, Hanlin Xiong, Yaoyao Xia, Zhifu Cui, Lingbin Liu
Share & cite
Links open in a new tab.
Citation record
- Year
- 2024
- Journal
- International Journal of Molecular Sciences
- WikiBiome key
bao-2024-iron-homeostasis-intestinal-immunity-gut-microbiota
Establishes iron homeostasis as a critical junction between host immunity (hepcidin-ferroportin axis) and microbiota composition—demonstrating how iron deficiency depletes Lactobacillus while iron excess enriches pathogenic Bacteroides and E. coli. This paper is foundational to WikiBiome's iron signatures across anemia, IBD, and metabolic disease.
Criteria met: 1 · 3 · 4Used in 24 visible records
microbeBifidobacterium→microbeEscherichia coli→metalIron→metalManganese→metalNickel→diseaseParkinson's Disease→mechanismAcidic Microenvironment→mechanismButyrate→mechanismCompetitive Exclusion→mechanismDefensins→defenseDietary Iron and Gut Ecology→defenseDyshomeostasis→defenseFerritin→defenseFerroportin→mechanismFerroptosis→mechanismGut Barrier Dysfunction→mechanismGut-Brain Axis→mechanismGut-Metal-Microbiome Interactions→mechanismGut Microbiome→defenseHepcidin→mechanismIndoles→defenseInnate Immunity→defenseInter-Kingdom Metal Shielding→defenseLactoferrin→Connect the evidence
Publicly readable discussion by ORCID-authenticated researchers. Questions, interpretation, methods, corrections, and new evidence stay attached to this record.
No discussion yet. Start with a precise question or a source-backed observation.
Activity and accepted changes
Accepted researcher context, editorial status, public discussion, and upstream Git revisions are shown together. Pending, declined, and withdrawn proposals remain private.
No public collaboration activity has been recorded for this page yet.