Toxicity, Mechanism and Health Effects of Some Heavy Metals
Monisha Jaishankar, Tenzin Tseten, Naresh Anbalagan, Blessy B. Mathew, Krishnamurthy N. Beeregowda
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- Year
- 2014
- Journal
- Interdisciplinary Toxicology
- WikiBiome key
jaishankar-2014-heavy-metal-toxicity-mechanisms
Unifies diverse metal toxicity mechanisms (ROS generation, glutathione depletion, mis-metallation, DNA repair inhibition) under a single conceptual framework, enabling WikiBiome to explain why multiple metals—arsenic, lead, cadmium, chromium—converge on dysbiotic inflammation. Critical for understanding why metal burden correlates with dysbiosis across metabolic, autoimmune, and neurological conditions.
Criteria met: 2 · 3 · 4 · 5Used in 24 visible records
diseaseAlzheimer's Disease→metalArsenic→diseaseAutism Spectrum Disorder→microbeBorrelia→metalCalcium→metalChromium→diseaseCirrhosis→diseaseDepression→diseaseDermatitis Herpetiformis→diseaseGastric Cancer→diseaseHepatitis→metalLead→metalMagnesium→metalMercury→metalNickel→metalSelenium→metalVanadium→mechanismDNA Damage in Metal Carcinogenesis→mechanismChelation Therapy→mechanismDevelopmental Metal Vulnerability: Critical Windows of Susceptibility→mechanismEDTA→mechanismEndocrine Disruptors→mechanismEnvironmental Metal Exposure→mechanismEpigenetics→Connect the evidence
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