WikiBiomeThe human microbiome encyclopediaRanked matches across titles, topics, categories, and article introductions.
Polyphenols are a diverse class of plant-derived compounds characterized by multiple phenol structural units. They are among the most abundant antioxidants in the human diet, found in fruits, vegetables, tea, coffee, wine, chocolate, and spices. What makes polyphenols p…
A chronic, relapsing-remitting inflammatory bowel disease (IBD) characterized by transmural inflammation of the gastrointestinal tract, most commonly affecting the terminal ileum and colon but capable of involving any segment from mouth to anus zhang 2017 intestinal mic…
Curcumin is discussed across 4 sources in the WikiBiome vault as a potential intervention. Triangle evidence linking this intervention to specific conditions needs to be populated from the source literature.
A Gram-positive obligate anaerobe in the family Ruminococcaceae (Clostridium cluster IV) whose defining metabolic activity is the degradation of dietary flavonoids — the very polyphenols that serve as anti-inflammatory, antioxidant, and antimicrobial agents. When Flavon…
A group 13 post-transition metal (atomic number 31) with no known biological function in any organism — yet one of the most promising antimicrobial metals precisely because of what it cannot do. Ga3+ is nearly identical to Fe3+ in ionic radius (0.62 Å vs 0.645 Å) and co…
Gordonibacter is a genus of Gram-positive, strictly anaerobic gut bacteria within the phylum Actinobacteria. It is recognized as a key participant in polyphenol metabolism, producing bioactive metabolites including equol (from dietary isoflavones) and urolithins (from e…
Gordonibacter urolithinfaciens is a Gram-positive, obligate anaerobic bacterium belonging to the family Eggerthellaceae that plays a specialized and critical role in polyphenol metabolism and conversion of ellagic acid to urolithin A. This microbial conversion is one of…
Adherence to the Alternate Mediterranean Diet (AMED) pattern — high in fiber, polyphenols, omega-3 fatty acids, and plant-based foods — as both a preventive and post-diagnosis survival strategy. This is the only dietary pattern with direct overall survival data in OC.
Non-digestible food substrates that selectively stimulate the growth and/or activity of beneficial gut microorganisms, conferring health benefits to the host. Distinct from probiotics (live organisms) and postbiotics (microbial metabolic products), prebiotics act as fue…
Research summary — not medical advice. This page synthesizes published research on a mechanism-level intervention. It is not a clinical recommendation. Consult a qualified healthcare provider before making any changes to diet, supplementation, or treatment.
Resveratrol is discussed across 5 sources in the WikiBiome vault as a potential intervention. Triangle evidence linking this intervention to specific conditions needs to be populated from the source literature.
Type 1 diabetes is an autoimmune disease in which immune-mediated destruction of insulin-producing beta cells in the pancreatic islets of Langerhans leads to lifelong insulin dependence. T1D is fundamentally distinct from type 2 diabetes, which is characterized by insul…