Impact of heavy metals on breast cancer (Review)
Ali AS, Nazar ME, Mustafa RM, Hussein S, Qurbani K, Ahmed SK
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- Year
- 2024
- Journal
- World Academy of Sciences Journal
- WikiBiome key
ali-2024-heavy-metals-breast-cancer-review
Establishes a metal-specific biomarker signature in breast cancer: copper accumulation (especially metastatic), cadmium elevation (endocrine disruption via ERα), zinc/manganese depletion (immune deficiency), and nickel/lead as metalloestrogens. WikiBiome depends on this evidence to explain how metal burden drives both nutritional immunity dysregulation and estrogen-dependent dysbiosis—linking metallomics to the estrobolome pathway across endocrine cancers.
Criteria met: 2 · 3 · 4Used in 10 visible records
diseaseBreast Cancer→metalCopper→metalNickel→metalZinc→mechanismDNA Damage in Metal Carcinogenesis→mechanismEndocrine Disruptors→mechanismMetal Carcinogenesis→mechanismMetalloestrogens→analysisDietary Metal Paradoxes: When Healthy Foods and Good Intentions Backfire→analysisMetal-Disease Matrix: A Cross-Source Synthesis→Connect the evidence
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