WikiBiomeThe human microbiome encyclopediaRanked matches across titles, topics, categories, and article introductions.
Low-carbohydrate diets reduce esophageal acid exposure time from 5.1% to 2.5% (P=0.022) by decreasing gastric distension and transient lower esophageal sphincter relaxations (TLESRs). Critically, benefits are independent of weight loss.
Research summary — not medical advice. This page synthesizes published research on a mechanism-level intervention. It is not a clinical recommendation. Consult a qualified healthcare provider before making any changes to diet, supplementation, or treatment.
Bacteroides is the most abundant genus in the Western adult gut and a cornerstone of intestinal polysaccharide metabolism. As members of the bacteroidetes phylum, Bacteroides species encode enormous repertoires of carbohydrate-active enzymes (CAZymes) organized into pol…
Bacteroides thetaiotaomicron is one of the most abundant and metabolically versatile commensals of the human gut, routinely cited as a model organism for studying host-microbe symbiosis. Its genome was one of the first human gut bacterial genomes fully sequenced, and su…
Bacteroidetes (recently reclassified as Bacteroidota) is one of the two dominant bacterial phyla in the human gut, together with firmicutes typically comprising 90% of the intestinal microbiota. Bacteroidetes are Gram-negative, obligately anaerobic, non-spore-forming ro…
Fermentative metabolism is the set of anaerobic metabolic pathways by which bacteria break down carbohydrates and amino acids in the absence of oxygen, producing short-chain fatty acids (SCFAs) (primarily butyrate, propionate, acetate), gases (H₂, CO₂, CH₄), and organic…
Ketone bodies (beta-hydroxybutyrate [BHB], acetoacetate, acetone) are produced by hepatic fatty acid oxidation during carbohydrate restriction, fasting, or ketogenic diet consumption. BHB is the most abundant and is structurally and functionally analogous to butyrate — …
Megamonas is a genus of obligate anaerobic, Gram-negative bacteria in the family Veillonellaceae (class Negativicutes, phylum Firmicutes). The type species is Megamonas hypermegale, with M. funiformis also well-characterized. It is a common member of the human gut micro…
A Gram-negative obligate anaerobe that occupies a unique context-dependent niche in the human gut microbiome. P. copri is significantly enriched in rheumatoid arthritis patients and is associated with metabolic syndrome and obesity, yet in other contexts it can function…
Saccharolytic fermentation is the microbial breakdown of carbohydrates (dietary fiber, resistant starch, host glycans) to produce short chain fatty acids (acetate, propionate, butyrate) and gases (H₂, CO₂, CH₄). It is the beneficial fermentation mode — the metabolic act…