Serum Levels of Selenium, Zinc, Copper, Manganese, and Iron in Prostate Cancer Patients
Saleh A. K. Saleh, Heba M. Adly, Altaf A. Abdelkhaliq, Anmar M. Nassir
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- Year
- 2020
- Journal
- Current Urology
- WikiBiome key
saleh-2020-serum-trace-elements-prostate-cancer
Characterizes the prostate cancer metallomic signature—Se/Zn/Mn depletion paired with Cu/Fe elevation—and establishes Cu-Zn competitive antagonism at the metallothionein level as a carcinogenic mechanism. WikiBiome depends on this evidence to recognize the pan-cancer metal pattern (Cu accumulation + Zn loss) as a cross-condition marker and to understand how metal dysregulation enables malignant transformation across tissue types.
Criteria met: 1 · 3 · 4 · 5Used in 10 visible records
metalCopper→metalIron→metalManganese→metalSelenium→metalZinc→mechanismCopper Dysregulation→mechanismMetal Carcinogenesis→mechanismMetallomics→mechanismMetallothionein→analysisMetal-Disease Matrix: A Cross-Source Synthesis→Connect the evidence
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