WikiBiomeThe human microbiome encyclopediaRanked matches across titles, topics, categories, and article introductions.
Cyclooxygenase-2 (COX-2) is the inducible enzyme that converts arachidonic acid to prostaglandin H₂ — the precursor of prostaglandin E₂ (PGE₂), prostacyclin, and thromboxane. Unlike COX-1 (constitutive, homeostatic), COX-2 is transcriptionally induced by nf kappa b duri…
Research summary — not medical advice. This page synthesizes published research on a mechanism-level intervention. It is not a clinical recommendation. Consult a qualified healthcare provider before making any changes to diet, supplementation, or treatment.
Mortierella is a genus of soil-dwelling fungi in the phylum Mortierellomycota (formerly placed in Zygomycota). While primarily known as environmental saprotrophs, Mortierella species have recently been identified as residents of the human gut mycobiome -- the fungal com…
Omega-3 fatty acids — eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) — are anti-inflammatory polyunsaturated fatty acids that counterbalance the pro-inflammatory effects of omega-6 arachidonic acid. They act through multiple mechanisms: competitive COX-2/5-L…
Polyunsaturated fatty acids (PUFAs) are fatty acids with multiple double bonds, divided into omega-3 (EPA, DHA, ALA) and omega-6 (arachidonic acid, linoleic acid) families. The omega-6:omega-3 ratio determines inflammatory tone — Western diets (~15:1) favor pro-inflamma…