Ten selected Sphingobium rods appear in eight groups: six singles and two touching pairs.
Genus representative reconstruction Editorially reviewed

Type-species-anchored Sphingobium reconstruction with ten slender rods. Representative, non-universal, non-diagnostic, and not a micrograph; omitted appendages make no genus-wide motility claim.

WikiBiome / Microbiome MedicineCurrent-genus-taxonomy-, type-species-, type-strain-, and output-audit-informed reconstruction
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Sphingobiumtaxon · genus
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Editorial review completeIdentifiers authority-verified · Accessibility validated · · sphingobium|sphingobium-morphology-v1.webp
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Sphingobium is a genus of Gram-negative, aerobic bacteria within the family Sphingomonadaceae. Primarily known as environmental organisms capable of degrading aromatic compounds, Sphingobium species have been unexpectedly identified in human microbiome studies of the reproductive tract and gut.

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01
Disease Associations

In endometriosis, Sphingobium is enriched in peritoneal fluid, representing one of the non-classical microbiome niches where bacterial communities contribute to local inflammatory environments (). Its presence in this typically sterile compartment raises questions about bacterial translocation and the breakdown of mucosal barriers in endometriotic disease.

02
Disease Associations

Sphingobium has also been detected in metagenomic profiling of gut microbiota associated with colorectal adenoma () and in studies of the gut microbiota's influence on male reproductive function ().

Contents1. Disease Associations2. Cross-References

Disease Associations#

In endometriosis, Sphingobium is enriched in peritoneal fluid, representing one of the non-classical microbiome niches where bacterial communities contribute to local inflammatory environments ([1]Microbiota composition and distribution along the female reproductive tract of women with endometriosisWei W, Zhang X, Tang H et al. · 2020Open reference 1).

Its presence in this typically sterile compartment raises questions about bacterial translocation and the breakdown of mucosal barriers in endometriotic disease.

Sphingobium has also been detected in metagenomic profiling of gut microbiota associated with colorectal adenoma ([2]Metagenomic Analyses of the Gut Microbiota Associated with Colorectal AdenomaSaito K, Koido S, Odamaki T et al. · 2019Open reference 2) and in studies of the gut microbiota's influence on male reproductive function ([3]Cai 2022 — Gut Microbiota Supports Male Reproduction via Nutrition, Immunity, and SignalingHui Cai, Xuanhong Cao, Dezhe Qin et al. · 2022Open reference 3).

Cross-References#

  • Endometriosis—peritoneal fluid enrichment
  • Colorectal Cancer—adenoma-associated gut microbiota
  • Gut-Testis Axis—gut microbiota and male reproduction
  • bacterial translocation—barrier breakdown enabling non-gut organisms in sterile sites
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References 3

Numbered by first appearance in the article, then reconciled with its declared source list.

  1. 1

    Wei W, Zhang X, Tang H et al. (2020). Microbiota composition and distribution along the female reproductive tract of women with endometriosis. Annals of Clinical Microbiology and Antimicrobials.

  2. 2

    Saito K, Koido S, Odamaki T et al. (2019). Metagenomic Analyses of the Gut Microbiota Associated with Colorectal Adenoma. PLOS ONE.

  3. 3

    Hui Cai, Xuanhong Cao, Dezhe Qin et al. (2022). Cai 2022 — Gut Microbiota Supports Male Reproduction via Nutrition, Immunity, and Signaling. Frontiers in Microbiology.

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