Lactobacillaceae

Lactobacillaceae is the family containing the genus Lactobacillus and related genera. It is the dominant family in the healthy vaginal microbiome and a significant family in the gut.

Family-level depletion is reported across schizophrenia,^{[1]The Gut Microbiome and Schizophrenia: The Current State of the Field and Clinical ApplicationsSzeligowski T, Yun AL, Lennox BR et al. · 2020Open reference 1 ↓[2]Alterations of the Gut Microbiota in Patients with SchizophreniaLi Z, Tao X, Wang D et al. · 2024Open reference 2 ↓} endometriosis,^{[3]Molecular detection of intrauterine microbial colonization in women with endometriosisKhan KN, Fujishita A, Masumoto H et al. · 2016Open reference 3 ↓} male reproductive dysfunction,^{[4]Lv 2024 — Gut Microbiota Is Involved in Male Reproductive Function: A ReviewShuya Lv, Jingrong Huang, Yadan Luo et al. · 2024Open reference 4 ↓} and endometrial cancer.^{[5]Yang 2025 — The Causal Relationship Between the Gut Microbiota and Endometrial Cancer: A Mendelian Randomization StudyChunyan Yang, Luolan Qin, Ling Li et al. · 2025Open reference 5 ↓}

For species-level detail, see Lactobacillus, Lactobacillus reuteri, Lactobacillus acidophilus, Lactobacillus gasseri, Lactobacillus jensenii.