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Search: “toll-like-receptor”

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I
Host defenses6 sources

Innate Immunity

Innate immunity is the body's first-line, non-specific defense against pathogens — comprising physical barriers (epithelium, mucus), antimicrobial molecules (calprotectin, lactoferrin, defensins), pattern recognition receptors (TLRs, NOD-like receptors), and phagocytic

T
Mechanisms9 sources

TLR4

Toll-like receptor 4 (TLR4) is a cell-surface pattern-recognition receptor in the toll like receptors family. It is best known for detecting particular forms of bacterial lipopolysaccharide (LPS) through a receptor complex and converting that detection into innate immun