STOP: Broad-Spectrum Antibiotics During Ovarian Cancer Chemotherapy
Harm potential: RED — Following this STOP inappropriately could delay life-saving antibiotic therapy.
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Harm potential: RED — Following this STOP inappropriately could delay life-saving antibiotic therapy.

Lactobacillus acidophilus is one of the most widely used probiotic species, with clinical trial evidence spanning multiple conditions. It is a component of many multi-strain probiotic formulations and has been tested in RCTs for schizophrenia, breast cancer chemotherapy…

Ovarian cancer is the most lethal gynecological malignancy, with approximately 314,000 new cases and 207,000 deaths annually worldwide. Its poor prognosis stems largely from late-stage diagnosis (70% at stage III/IV) and the development of chemoresistance. From a metall…

Pancreatic cancer is the fifth leading cause of cancer death in Western nations, with rising incidence globally. Pancreatic ductal adenocarcinoma (PDAC) accounts for over 90% of cases. Five-year survival remains approximately 12%, owing to late-stage diagnosis, aggressi…

A dense, chemically inert noble metal with no known biological function -- yet platinum compounds are the backbone of chemotherapy for ovarian, testicular, lung, and bladder cancers. The discovery that cisplatin inhibits bacterial cell division (Rosenberg, 1965) led to …