WikiBiomeThe human microbiome encyclopediaRanked matches across titles, topics, categories, and article introductions.
Oxalobacter formigenes is an obligate anaerobic, Gram-negative bacterium that occupies a unique metabolic niche in the human gut as the primary oxalate-degrading specialist. Its loss from the gut microbiome — most commonly from antibiotic exposure — has cascading conseq…
The most abundant mineral in the human body, with ~99% stored in bones and teeth. Calcium's biological significance extends far beyond structural support -- it is the universal second messenger in cell signaling, controlling neurotransmitter release, muscle contraction,…
Oxalate (oxalic acid) is a dietary compound (spinach, rhubarb, nuts, chocolate) and endogenous metabolic end-product that forms insoluble calcium oxalate crystals — the primary component of ~80% of kidney stones. The gut microbiome is the primary route of oxalate degrad…
Oxalate (ethanedioic acid, C2O4^2-) is a small dicarboxylic acid found in many plant foods that has outsized significance for mineral metabolism and kidney health. In the gut, oxalate's fate is determined by a single specialist bacterium -- Oxalobacter formigenes -- who…